There is no such thing as semi-permanent moles, moles are permanent, they don't naturally disappear. Once they're formed, they only disappear if you remove them. Actually, not all the reasons for cell clusterings are known. An melanogenesis is the production and release of melanin. So melanogenesis is not a process that needs to be triggered. Those things effect malonogenesis, but malanogenesisis is an on going normal process anyway.
OOC: Moles are made when the cells in the skin grow in a cluster instead of being spread throughout the skin. They don't need to move to form a cluster. The cells are called melanocytes, moles are not mylanocytes. Mylanocytes are pigment forming cells, that cause moles. The mole itself is not a mylanocyte, the same applies to freckles.
There are two ways to start melanogenesis in melanocytes. Vitamin D, retinoids, certain hormones and UV exposure all stimulate melanocytes to the point where they undergo melanogenesis and darken the skin. In some cases, this is the impermanent tan or freckle. In other cases, it is the semi-permanent mole. That is where a mole comes from. Getting punctured in anyway does not cause a mole. It causes a scar.




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