The Facts - There WILL be at least one more entry in the compilation, the Director to CC said as much in an interview on 1up.com.

My opinion - I also doubt that Genesis will be the villian since, in a translation of the FFVII Ultimanium, Nomura said that Genesis' dialog at the end of DoC refers to him protecting the planet, rather than causing destruction.

That would leave just one question - who'd be the villian?