Naked Lunch. I've seen some weird movies but this is the strangest one yet.

An exterminator gets addicted to the stuff he kills the bugs with, accidentally kills his wife, runs away to an imaginary country, and writes a book about his adventures there. He also gets involved with a secret organization and a few different drug pushers, accidentally feeds a gay local to a centipede man, has conversations with his type writers, which happen to be living creatures in charge of said secret organization, and kills his wife's doppleganger in the same way he did her in the first time. He also can't seem to decide if he's gay or not and there's an amusing story of a talking butthole.

Weird flick, I give it an 8.