I have acquired both the Paragon and Renegade achievements.
Renegade tends to be a bit inconsistent at times, as a Renegade Shepard seems to make it his life's worth to piss off everyone, regardless of actual views or standpoints. So one minute you'll be arguing about how non-humans are scum, and the next you'll be telling Ashley to stop bitching about the non-humans.
Paragon is a lot more consistent, because you are generally being the same goody-goody to everyone, and your responses tend to reflect that. You actually tend to take a middle ground in most of the arguments, understanding other people's views, and accepting them, but not necessarily endorsing them.
So I wind up playing Paragon a bit more than I play Renegade, but there are certainly some enjoyable moments on the Renegade side.
Although, I have to say, there are a couple Renegade choices I never pick. Udina is never my choice for Councilor, and I never acquire Morinth in ME2 (past the one time to get Dominate). Those decisions make no sense from either viewpoint.



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