Ah. In that case, it really depends on the game and what I want to do with it. With brand new games I like to get 100%, but if I'm playing the old games (eg. FFI-XII) I don't, because I don't get a trophy for it. For some of the old games I've probably done 100% anyway.

As for how much help I need from guides - generally I need a decent amount if I want to 100% the game. Especially if I there are missable items or something (one of my massive pet peeves - missable items are a horrible, terrible thing).