I haven't read anything about Binding of Isaac before, but just now I read this review by Pokemaster73 on Steam:

YOU ARE A YOUNG NAKED BOY WHO SHOOTS SPOOKY MONSTERS IN THE BASEMENT WITH YOUR TEARS
IT DOESN'T GET ANY BETTER THAN THIS
THIS GAME IS LIKE ZELDA ON CRACK
IF YOU DON'T BUY THIS GAME YOU'RE MISSING OUT, MAN
So now my vote is for Binding of Isaac.