Guitarists:

David Gilmour - Pink Floyd
John Frusciante - Red Hot Chili Peppers
Mike Einziger - Incubus
Mark Tremonti - Creed & Alterbridge

If I was to pick one then David Gilmour would be it.

Drummers:

Nick Mason - Pink Floyd
Chad Smith - Red Hot Chili Peppers
Jose Pasillas - Incubus

Jose Pasillas would probably be my pick here due to the drum solo I saw him perform while looking up live concerts on the net.