Is it really that interesting? I've always just used a cure disease potion when inflicted, or avoided vampires entirely. I might just check it out though. At the moment, I'm playing my third playthrough - as an Imperial. I use a mixture of a bow, sword and dagger in combat; relying on stealth to get a critical attack from the first strike.

I haven't done any quests yet though - saving them for level 25+ since the rewards are better at higher levels.