I am of the opinion that the best way for me to make female friends and no longer be a lonely virgin is to comment about every female I ever come across as though I have never met one of these mythical beings before, and to obnoxiously comment on the fact that they are female (Women aren't generally smart enough to identify this fact, after all!) and ask whether they are available, attractive (They sound it!), and interested.
It has not worked yet but I am sure it will one day.
(PS: I once was waiting for the round to start in Halo 3 when some dude starts some lighthearted abuse at me. I don't say anything, but after a moment he stops talking, and I hear a voice in the background. He then replies to her "Well of course I don't know him, that's why I'm being a dick!" It's mostly just the nature of the beast.)