Let's make this a general Fallout 3 thread just to spite Stu even further.

The Dismemberer is the greatest weapon in the history of video games. y/n?

EDIT: Although the Experimental MIRV is a good candidate. I killed everyone in Megaton, made their corpses into a huge pile, then fired my MIRV at it repeatedly. What I was left with were a bunch of tiny flesh-coloured marbles, each reading things like "Search Lucas Simms" and "Search Megaton Settler". Much more satisfying than helping Burke