As for setting, my best guess would be Kooluk. If it's not, I'd say it'll be somewhere pretty left-field and unlikely; either somewhere we've not heard of before, or somewhere oddball that we know almost nothing about, like Kanakan or Zelant. I don't think it'll be New Armes mainly because they obviously weren't reformed before V, and after the events of V they're said to have become more moderate and friendlier. Though obviously later on there could be a reaction against this

But I think Kooluk is the most likely setting 'cause it's pretty well established to be in a pretty poor state. I'm not sure Harmonia will ever be the subject of a Suikoden; if it is then I'd say not until very late in the series.